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The
Science of Xanthones
Okay,
so we know XanGo® Juice boasts a proprietary whole-fruit
formula, harnessing a concentrated rush of xanthones.
.
But here’s the straight scoop.
Understanding
the Research Behind this Potent Antioxidant, the Nutritional
Firepower in XanGo® Juice
Antioxidant
Power of Xanthones
A
powerful antioxidant, xanthones are a family of vigorous
phytonutrients. Research supports the role of xanthones
in minor muscle pain, immune system support, joint flexibility
and intestinal health.*
 Previous
studies and ongoing research recognize xanthones for
the following health benefits:
Bolstering
of the cell’s defense against free radicals in
the body and maintenance of cell integrity.9-12*
Support of a healty immune system.4, 6-8*
Support of cartilage and joint function and flexibility.13-16*
Maintenance of intestinal ? ora and regularity as well
as promotion of intestinal health.1-5*
Maintenance of a healthy seasonal respiratory system.14*
Nature’s Greatest Xanthone Source
The
mangosteen fruit, or Garcinia mangostana, is found primarily
in Southeast Asia. The mangosteen fruit is composed
of the rind (skin of the fruit), the pulp (four to eight
segments) and the seeds (usually two to three seeds).
Studies show the mangosteen is nature’s greatest
supply of xanthones, the highest concentration of which
resides in the fruit’s pericarp, which includes
the rind and the pulp.
According
to research, the mangosteen including the pericarp,
as found in XanGo® Juice, is the source of more
than 40 different xanthones.The pericarp of the mangosteen
was used in folk medicine for centuries to treat dysentery,
diarrhea and urinary tract infections and topically
to treat eczema and other skin/wound disorders. Traditionally,
the pericarp of the mangosteen fruit has been used to
control fever and ward off infections of every kind.
Though the fruit also was touted for its medicinal properties,
its divine taste made the mangosteen venerated.
Numerous
independent investigators have researched and reported
on the medicinal benefits of the mangosteen.
XanGo® Juice: A New
Category of Supplements is Born
Recognized
as a category creator, XanGo® Juice is a delicious
dietary supplement that harnesses the nutritional attributes
of the whole mangosteen fruit through a proprietary
formula.
Made
from an exclusive puree of the complete mangosteen fruit,
XanGo® Juice is a concentrated source of xanthones.
Research shows xanthones possess potent antioxidant
properties that may help achieve a healthy seasonal
respiratory system, boost immune-system health, promote
joint ? exibility and maintain intestinal health.*
Through
its exclusive whole-fruit mangosteen puree process,
XanGo captures the bene? ts of the entire fruit in its
market-leading XanGo® Juice. XanGo’s founders
referenced decades of mangosteen studies to support
their discovery of a singular dietary mangosteen supplement
with a sensational taste. One to three ounces each day
is recommended to unleash the power of xanthones in
XanGo® Juice.
*These
statements have not been evaluated by the FDA. This
product is not intended to diagnose, treat, cure or
prevent any disease.
*The Research
1. Begum N, Gopalakrishnan C, Subramanian S, Shankaranarayanan
D, Kameswaran L. Anti-ulcer and anti microbial activities
of Gartanin, a xanthone from Garcinia Mangostana Linn.
. Bull Islam. 1982;2(20):518-521
2.
Caius J. The Medicinal and Poisonous Plants of India.
Jodhpur, India: Scienti? c Publishers; 1986.
3.
Garnett M, Sturton S. G. mangostana in the treatment
of amoebic dysentery. Chines Med J. 1932;46(10):969-973
4.
Chopra R, Nayar S, Chopra I. Glossary of Indian Medicinal
Plants. New Delhi; 1956.
5.
Kirtikar K, Basu B. Indian Medicinal Plants. Vol 1.
Dehra Dun, India: International Book Distributors; 1999.
6.
Chanarat P, Chanarat N, Fujihara M, Nagumo T. Immunopharmacological
activity of polysaccharide from the pericarp of mangosteen
garcinia: phagocytic intracellular killing activities.
Journal of the Medical Association of Thailand - Chotmaihet
thangphaet J Med Assoc Thai. 1997/09// 1997;80 Suppl
1:S149-154.
7.
Chen SX, Wan M, Loh BN. Active constituents against
HIV-1 protease from Garcinia mangostana. Planta Med.
1996/08// 1996;62(4):381-382.
8.
Gopalakrishnan G, Banumathi B, Suresh G. Evaluation
of the antifungal activity of natural xanthones from
Garcinia mangostana and their synthetic derivatives.
J Nat Prod. 1997/05// 1997;60(5):519-524.
9.
Mahabusarakam W, Proudfoot J, Taylor W, Croft K. Inhibition
of lipoprotein oxidation by prenylated xanthones derived
from mangostin. Free Radic Res. 2000/11// 2000;33(5):643-659.
10.
Williams P, Ongsakul M, Proudfoot J, Croft K, Beilin
L. Mangostin inhibits the oxidative modi? cation of
human low density lipoprotein. Free Radic Res. 1995/08//
1995;23(2):175-184.
11.
Yoshikawa M, Harada E, Miki A, et al. Antioxidant constituents
from the fruit hulls of mangosteen. Yakugaku Zasshi.
1994;114(2):129-133.
12.
Leong L, Shui G. An investigation of antioxidant capacity
of fruits in Singapore markets. Food Chemistry. 2002;76:69-75.
13.
Nabandith V, Suzui M, Morioka T, et al. Inhibitory effects
of crude alpha-mangostin, a xanthone derivative, on
two different categories of colon preneoplastic lesions
induced by 1, 2-dimethylhydrazine in the rat. Asian
Pac J Cancer Prev. 2004;5(4):433-438.
14.
Nakatani K, Atsumi M, Arakawa T, et al. Inhibitions
of histamine release and prostaglandin E2 synthesis
by mangosteen, a Thai medicinal plant. Biol Pharm Bull.
2002/09// 2002;25(9):1137-1141.
15.
Nakatani K, Nakahata N, Arakawa T, Yasuda H, Ohizumi
Y. Inhibition of cyclooxygenase and prostaglandin E2
synthesis by gamma-mangostin, a xanthone derivative
in mangosteen, in C6 rat glioma cells. Biochem Pharmacol.
2002/01/01/ 2002;63(1):73-79.
16.
Nakatani K, Yamakuni T, Kondo N, et al. gamma-Mangostin
inhibits inhibitor-kappaB kinase activity and decreases
lipopolysaccharide-induced cyclooxygenase-2 gene expression
in C6 rat glioma cells. Mol Pharmacol. 2004;66(3):667-674.
*These
statements have not been evaluated by the FDA. This
product is not intended to diagnose, treat, cure or
prevent any disease
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 $49.95
US one bottle
 Note:
price for a single bottle includes a $10 shipping surcharge.
It costs $17 to ship a single bottle safely, so we must
add this surcharge to cover that cost. It is much better
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