"The healthiest juice in the world!" - Dr. Templeman

The Science of Xanthones

Okay, so we know XanGo® Juice boasts a proprietary whole-fruit formula, harnessing a concentrated rush of xanthones.

. But here’s the straight scoop.


Understanding the Research Behind this Potent Antioxidant, the Nutritional Firepower in XanGo® Juice


Antioxidant Power of Xanthones

A powerful antioxidant, xanthones are a family of vigorous phytonutrients. Research supports the role of xanthones in minor muscle pain, immune system support, joint flexibility and intestinal health.*


Previous studies and ongoing research recognize xanthones for the following health benefits:

Bolstering of the cell’s defense against free radicals in the body and maintenance of cell integrity.9-12*
Support of a healty immune system.4, 6-8*
Support of cartilage and joint function and flexibility.13-16*
Maintenance of intestinal ? ora and regularity as well as promotion of intestinal health.1-5*
Maintenance of a healthy seasonal respiratory system.14*
Nature’s Greatest Xanthone Source

The mangosteen fruit, or Garcinia mangostana, is found primarily in Southeast Asia. The mangosteen fruit is composed of the rind (skin of the fruit), the pulp (four to eight segments) and the seeds (usually two to three seeds). Studies show the mangosteen is nature’s greatest supply of xanthones, the highest concentration of which resides in the fruit’s pericarp, which includes the rind and the pulp.

According to research, the mangosteen including the pericarp, as found in XanGo® Juice, is the source of more than 40 different xanthones.The pericarp of the mangosteen was used in folk medicine for centuries to treat dysentery, diarrhea and urinary tract infections and topically to treat eczema and other skin/wound disorders. Traditionally, the pericarp of the mangosteen fruit has been used to control fever and ward off infections of every kind. Though the fruit also was touted for its medicinal properties, its divine taste made the mangosteen venerated.

Numerous independent investigators have researched and reported on the medicinal benefits of the mangosteen.


XanGo® Juice: A New Category of Supplements is Born

Recognized as a category creator, XanGo® Juice is a delicious dietary supplement that harnesses the nutritional attributes of the whole mangosteen fruit through a proprietary formula.

Made from an exclusive puree of the complete mangosteen fruit, XanGo® Juice is a concentrated source of xanthones. Research shows xanthones possess potent antioxidant properties that may help achieve a healthy seasonal respiratory system, boost immune-system health, promote joint ? exibility and maintain intestinal health.*

Through its exclusive whole-fruit mangosteen puree process, XanGo captures the bene? ts of the entire fruit in its market-leading XanGo® Juice. XanGo’s founders referenced decades of mangosteen studies to support their discovery of a singular dietary mangosteen supplement with a sensational taste. One to three ounces each day is recommended to unleash the power of xanthones in XanGo® Juice.

*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

*The Research

1. Begum N, Gopalakrishnan C, Subramanian S, Shankaranarayanan D, Kameswaran L. Anti-ulcer and anti microbial activities of Gartanin, a xanthone from Garcinia Mangostana Linn. . Bull Islam. 1982;2(20):518-521

2. Caius J. The Medicinal and Poisonous Plants of India. Jodhpur, India: Scienti? c Publishers; 1986.

3. Garnett M, Sturton S. G. mangostana in the treatment of amoebic dysentery. Chines Med J. 1932;46(10):969-973

4. Chopra R, Nayar S, Chopra I. Glossary of Indian Medicinal Plants. New Delhi; 1956.

5. Kirtikar K, Basu B. Indian Medicinal Plants. Vol 1. Dehra Dun, India: International Book Distributors; 1999.

6. Chanarat P, Chanarat N, Fujihara M, Nagumo T. Immunopharmacological activity of polysaccharide from the pericarp of mangosteen garcinia: phagocytic intracellular killing activities. Journal of the Medical Association of Thailand - Chotmaihet thangphaet J Med Assoc Thai. 1997/09// 1997;80 Suppl 1:S149-154.

7. Chen SX, Wan M, Loh BN. Active constituents against HIV-1 protease from Garcinia mangostana. Planta Med. 1996/08// 1996;62(4):381-382.

8. Gopalakrishnan G, Banumathi B, Suresh G. Evaluation of the antifungal activity of natural xanthones from Garcinia mangostana and their synthetic derivatives. J Nat Prod. 1997/05// 1997;60(5):519-524.

9. Mahabusarakam W, Proudfoot J, Taylor W, Croft K. Inhibition of lipoprotein oxidation by prenylated xanthones derived from mangostin. Free Radic Res. 2000/11// 2000;33(5):643-659.

10. Williams P, Ongsakul M, Proudfoot J, Croft K, Beilin L. Mangostin inhibits the oxidative modi? cation of human low density lipoprotein. Free Radic Res. 1995/08// 1995;23(2):175-184.

11. Yoshikawa M, Harada E, Miki A, et al. Antioxidant constituents from the fruit hulls of mangosteen. Yakugaku Zasshi. 1994;114(2):129-133.

12. Leong L, Shui G. An investigation of antioxidant capacity of fruits in Singapore markets. Food Chemistry. 2002;76:69-75.

13. Nabandith V, Suzui M, Morioka T, et al. Inhibitory effects of crude alpha-mangostin, a xanthone derivative, on two different categories of colon preneoplastic lesions induced by 1, 2-dimethylhydrazine in the rat. Asian Pac J Cancer Prev. 2004;5(4):433-438.

14. Nakatani K, Atsumi M, Arakawa T, et al. Inhibitions of histamine release and prostaglandin E2 synthesis by mangosteen, a Thai medicinal plant. Biol Pharm Bull. 2002/09// 2002;25(9):1137-1141.

15. Nakatani K, Nakahata N, Arakawa T, Yasuda H, Ohizumi Y. Inhibition of cyclooxygenase and prostaglandin E2 synthesis by gamma-mangostin, a xanthone derivative in mangosteen, in C6 rat glioma cells. Biochem Pharmacol. 2002/01/01/ 2002;63(1):73-79.

16. Nakatani K, Yamakuni T, Kondo N, et al. gamma-Mangostin inhibits inhibitor-kappaB kinase activity and decreases lipopolysaccharide-induced cyclooxygenase-2 gene expression in C6 rat glioma cells. Mol Pharmacol. 2004;66(3):667-674.

*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease







All AboutXanGo™
About Your Health In The News Business Opportunity
About XanGo™  New York Times on Mangosteen  Training Manual 
Why Drink Xango�: NutraUSA on XanGo Sign Up as a Distributor NOW 
Mangosteen... Queen of Fruits!  NewsTarget on XanGo Once-in-a-lifetime Opportunity 
History of Mangosteen XanGo Challenges Competitors Supplies and Teaching Tools
Xanthones and other Anti-Oxidants from the Mangosteen    XanGo Opens in Japan Financial Rewards   
 About the Company  XanGo® Juice Spotlight (pdf)
Mangosteen Money Tree 
The Company and the Team  XanGo Mangosteen Xanthones Research Why Network Marketing? 
Our Mission   Science and Research  XanGo Magic Success Manual 
XanGo™ Magic Team Newsletter  The Science of Xanthones Events and Meetings Calendar 
  Summaries of Studies   
Dr. Templeman: The X-Factor   


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